Ukukhishwa komugqa wokukhiqiza wenqubo eyomile ngaphandle kwe-DMF futhi iqukethe iphunga elimnandi, ama-ketones, i-lipids solvent, ukumuncwa kwamanzi ahlanzekile kulokho kusebenza kahle kwezinyibilikisi akubi, noma akukho mphumela.Inkampani ithuthukise inqubo entsha yokubuyisela i-solvent eyomile, eyashintshwa ngokwethulwa koketshezi lwe-ionic njengesimunyisi, ingagaywa kabusha kugesi yomsila wezinto ezincibilikayo, futhi inenzuzo enkulu kwezomnotho kanye nenzuzo yokuvikelwa kwemvelo.